Instability in the structure and number of chromosomes is a trait common to cells from most epithelial cancers. A role in chromosome segregation for a pathway previously implicated in the DNA damage response reveals new connections between the tumour suppressive processes that maintain chromosome integrity.
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Sato, K., Ohta, T. & Venkitaraman, A. A mitotic role for the DNA damage-responsive CHK2 kinase. Nat Cell Biol 12, 424–425 (2010). https://doi.org/10.1038/ncb0510-424
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DOI: https://doi.org/10.1038/ncb0510-424
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