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Killer wiles: growing interest in Fas

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Signalling pathways involved in axonal growth are the subject of intense study. A new report further highlights the role of the extracellular signal-regulated kinase (ERK)/p35 pathway, but identifies a surprising potential trigger: the death receptor Fas. This study illustrates the importance of cellular context in the functional outcome of a given signalling mechanism.

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Figure 1: Different functional outcomes from signalling through the Fas receptor.

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Authors and Affiliations

  1. the Developmental Biology Institute of Marseille (IBDM; CIIRS, INSERM) Campus de Luminy - Case 907, 13288, Marseille, Cedex 09, France

    Brigitte Pettmann & Christopher E. Henderson

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  1. Brigitte Pettmann
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  2. Christopher E. Henderson
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Pettmann, B., Henderson, C. Killer wiles: growing interest in Fas. Nat Cell Biol 5, 91–92 (2003). https://doi.org/10.1038/ncb0203-91

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