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Putting epigenome comparison into practice

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Comparative analysis of epigenomes offers new opportunities to understand cellular differentiation, mutation effects and disease processes. But the scale and heterogeneity of epigenetic data present numerous computational challenges.

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Figure 1: A proposed cyberinfrastructure for epigenome analysis and comparison.

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Authors and Affiliations

  1. Molecular and Human Genetics Department, Aleksandar Milosavljevic is at The NIH Epigenomics Roadmap Data Analysis and Coordination Center, Baylor College of Medicine, Houston, Texas, USA.,

    Aleksandar Milosavljevic

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  1. Aleksandar Milosavljevic
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Correspondence to Aleksandar Milosavljevic.

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Competing interests

The author is the founder of and owns shares in IP Genesis, Inc., a company that commercializes academically developed software for genomic and epigenomic research.

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Milosavljevic, A. Putting epigenome comparison into practice. Nat Biotechnol 28, 1053–1056 (2010). https://doi.org/10.1038/nbt1010-1053

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