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siRNA delivery not Toll-free

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Activating the tumor-associated immune system with an siRNA conjugated to a Toll-like receptor 9 ligand is a promising anticancer strategy.

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Figure 1: TLR9-mediated RNAi in the tumor microenvironment.

Kim Caesar

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Authors and Affiliations

  1. Michael P. Gantier and Bryan R.G. Williams are at the Centre for Cancer Research, Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia.,

    Michael P Gantier & Bryan R G Williams

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  1. Michael P Gantier
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  2. Bryan R G Williams
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Correspondence to Bryan R G Williams.

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Gantier, M., Williams, B. siRNA delivery not Toll-free. Nat Biotechnol 27, 911–912 (2009). https://doi.org/10.1038/nbt1009-911

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