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New enzymes for “warheads”

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Characterization of novel multifunctional proteins involved in assembly of the enediyne natural products C-1027 and calicheamicin furthers the potential of combinatorial biosynthesis.

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Figure 1: The diversity of polyketide synthases (PKSs) from bacteria and fungi.

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Authors and Affiliations

  1. professor in the Department of Microbiology and BioTechnology Institute, University of Minnesota and a member of the Scientific Advisory Board of Acera Biosciences, Minneapolis, 55455, MN

    David H. Sherman

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  1. David H. Sherman
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Sherman, D. New enzymes for “warheads”. Nat Biotechnol 20, 984–985 (2002). https://doi.org/10.1038/nbt1002-984

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