Random peptide libraries displayed in the viral capsid enable the selection of AAV vectors for targeted gene delivery.
References
Muller, O.J. et al. Nat. Biotechnol. 21, 1040–1046 (2003).
Perabo, L. et al. Mol. Ther. 8, 151–157 (2003).
Xie, Q. et al. Proc. Natl. Acad. Sci. USA 99, 10405–10410 (2002).
Bartlett, J.S., Kleinschmidt, J., Boucher, R.C. & Samulski, R.J. Nat. Biotechnol. 17, 181–186 (1999).
Girod, A. et al. Nat. Med. 5, 1052–1056 (1999).
Nicklin, S.A. et al. Mol. Ther. 4, 174–181 (2001).
Grifman, M. et al. Mol. Ther. 3, 964–975 (2001).
Virnekas, B. et al. Nucleic Acids Res. 22, 5600–5607 (1994).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lieber, A. AAV display—homing in on the target. Nat Biotechnol 21, 1011–1013 (2003). https://doi.org/10.1038/nbt0903-1011
Issue Date:
DOI: https://doi.org/10.1038/nbt0903-1011
- Springer Nature America, Inc.
This article is cited by
-
Design and construction of targeted AAVP vectors for mammalian cell transduction
Nature Protocols (2007)