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Metabolic engineering without plasmids

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Tandem gene duplication is harnessed to genetically engineer Escherichia coli, enabling sustained expression of metabolic products.

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Figure 1: CIChE addresses the productivity loss caused by allele segregation.

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Authors and Affiliations

  1. Aashiq H. Kachroo, Makkuni Jayaram & Paul A. Rowley are at the University of Texas at Austin, Austin, Texas, USA.,

    Aashiq H Kachroo, Makkuni Jayaram & Paul A Rowley

Authors
  1. Aashiq H Kachroo
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  2. Makkuni Jayaram
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  3. Paul A Rowley
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Correspondence to Paul A Rowley.

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Kachroo, A., Jayaram, M. & Rowley, P. Metabolic engineering without plasmids. Nat Biotechnol 27, 729–731 (2009). https://doi.org/10.1038/nbt0809-729

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