A near-infrared fluorescent protein opens a window into the mammalian body.
References
Giepmans, B.N., Adams, S.R., Ellisman, M.H. & Tsien, R.Y. Science 312, 217–224 (2006).
Chalfie, M., Tu, Y., Euskirchen, G., Ward, W.W. & Prasher, D.C. Science 263, 802–805 (1994).
Contag, C.H. et al. Photochem. Photobiol. 66, 523–531 (1997).
Takada, T. et al. Nat. Biotechnol. 15, 458–461 (1997).
Chishima, T. et al. Cancer Res. 57, 2042–2047 (1997).
Zhao, H. et al. J. Biomed. Opt. 10, 41210 (2005).
Fischer, A.J. & Lagarias, J.C. Proc. Natl. Acad. Sci. USA 101, 17334–17339 (2004).
Shu, X. et al. Science 324, 804–807 (2009).
Rasmussen, J.C., Tan, I.C., Marshall, M.V., Fife, C.E. & Sevick-Muraca, E.M. Curr. Opin. Biotechnol. 20, 74–82 (2009).
Shcherbo, D. Biochem. J. 418, 567–574 (2009).
Troy, T., Jekic-McMullen, D., Sambucetti, L. & Rice, B. Mol. Imaging 3, 9–23 (2004).
Zacharakis, G., Shih, H., Ripoll, J., Weissleder, R. & Ntziachristos, V. Mol. Imaging 5, 153–159 (2006).
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Rice, B., Contag, C. The importance of being red. Nat Biotechnol 27, 624–625 (2009). https://doi.org/10.1038/nbt0709-624
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DOI: https://doi.org/10.1038/nbt0709-624
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