Insulin-producing cells generated from human embryonic stem cells protect mice from diabetes.
References
Ricordi, C. & Strom, T. Nat. Rev. Immunol. 4, 259–268 (2004).
Kroon, E. et al. Nat. Biotechnol. 26, 443–452 (2008).
Kubo, A. et al. Development 131, 1651–1662 (2004).
D'Amour, K.A. et al. Nat. Biotechnol. 23, 1534–1541 (2005).
McLean, A.B. et al. Stem Cells 25, 29–38 (2007).
D'Amour, K.A. et al. Nat. Biotechnol. 24, 1392–1401 (2006).
Yang, H. & Wright, J.R. Jr. Endocrinology 143, 2491–2495 (2002).
Fornoni, A. et al. Diabetologia 51, 298–308 (2008).
Osafune, K. et al. Nat. Biotechnol. 26, 313–315 (2008).
Yazawa, K., Fisher, W.E. & Brunicardi, F.C. World J. Surg. 26, 783–789 (2002).
Schuldiner, M., Itskovitz-Eldor, J. & Benvenisty, N. Stem Cells 21, 257–265 (2003).
Fareed, M.U. & Moolten, F.L. Gene Ther. 9, 955–962 (2002).
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H.E. is a cofounder, shareholder and consultant of the unlisted biotech company Betagenon AB, Sweden.
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Ricordi, C., Edlund, H. Toward a renewable source of pancreatic β-cells. Nat Biotechnol 26, 397–398 (2008). https://doi.org/10.1038/nbt0408-397
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DOI: https://doi.org/10.1038/nbt0408-397
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