Peptide chips enable quantitative analysis of protein kinase activity and should facilitate the search for novel classes of protein kinase inhibitors.
References
Plowman, G.D. et al. Proc. Natl. Acad. Sci. USA 96, 36603–13610 (1999).
Houseman, B.T., Huh, J.H., Kron, S.J. & Mrksich, M. Nat. Biotechnol. 20, 270–274 (2002).
Schlessinger, J. Cell 103, 211–225 (2000).
Zheng J. et al. Biochemistry 32, 2154–2161 (1993).
Mohammadi, M. et al. Science 276, 955–960 (1997).
Mohammadi, M. et al. EMBO J. 17, 5896–5904 (1998).
Mrksich, M. & Whitesides, G.M. Annu. Rev. Biophy. Biomol. Structure 25, 55–78 (1996).
Zhu, H. et al. Science 293, 2101–2105 (2001).
Zhu, H. et al. Nature Genet. 26, 283–299 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Schlessinger, J. A solid base for assaying protein kinase activity. Nat Biotechnol 20, 232–233 (2002). https://doi.org/10.1038/nbt0302-232
Issue Date:
DOI: https://doi.org/10.1038/nbt0302-232
- Springer Nature America, Inc.
This article is cited by
-
A resettable dynamic microarray device
Biomedical Microdevices (2011)