References
Ashburner, M. et al. Nat. Genet. 25, 25–29 (2000).
Davis, D.A., Ciurea, I., Flanagan, T.M. & Perrier, L. Med. J. Aust. 180, S68–S71 (2004).
Camon, E. et al. Nucleic Acids Res. 32, D262–D266 (2004).
Harris, M. et al. Nucleic Acids Res. 32, D258–D261 (2004).
Subramanian, A. et al. Proc. Natl. Acad. Sci. USA 102, 15545–15550 (2005).
Doniger, S.W. et al. Genome Biol. 4, R7 (2003).
Al-Shahrour, F., Diaz-Uriarte, R. & Dopazo, J. Bioinformatics 20, 578–580 (2004).
Alterovitz, G., Xiang, M., Mohan, M. & Ramoni, M.F.G.O. Nucleic Acids Res. 35, D322–D327 (2007).
Ogren, P.V., Cohen, K.B. & Hunter, L. Pac. Symp. Biocomput. 174–185 (2005).
Dennis, G. Jr. et al. Genome Biol. 4, 3 (2003).
Zhou, M. & Cui, Y. In Silico Biol. 4, 323–333 (2004).
Raychaudhuri, S., Chang, J.T., Sutphin, P.D. & Altman, R.B. Genome Res. 12, 203–214 (2002).
MacKay, D.J.C. Information Theory, Inference, And Learning Algorithms, xii (Cambridge University Press, Cambridge, U.K.; New York, 2003).
Wu, C.H. et al. Nucleic Acids Res. 34, D187–D191 (2006).
The Gene Ontology Consortium. Nucleic Acids Res. 36, D440–D444 (2008).
Yi, Y., Li, C., Miller, C. & George, A.L. Jr. Genome Biol. 8, R133 (2007).
Gkoutos, G.V. et al. Comp. Funct. Genomics 5, 545–551 (2004).
Smith, B. et al. Nat. Biotechnol. 25, 1251–1255 (2007).
Acknowledgements
This work was supported in part by the National Library of Medicine (NLM/NIH) under grants 1K99LM009826 and 5T15LM007092 and by the National Human Genome Research Institute (NHGRI/NIH) under grants 2P41HG02273, 1R01HG003354, and 1R01HG004836. The authors are grateful to the anonymous reviewers for their helpful suggestions.
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Alterovitz, G., Xiang, M., Hill, D. et al. Ontology engineering. Nat Biotechnol 28, 128–130 (2010). https://doi.org/10.1038/nbt0210-128
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DOI: https://doi.org/10.1038/nbt0210-128
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