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Enriching quantitative proteomics with SIN

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A new metric called the normalized spectral index (SIN) provides a simple way to quantify and compare label-free proteomics data.

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Figure 1: The normalized spectral index (SIN) leverages unique peptide numbers, spectral counts and fragment ion-intensities to determine protein abundances.

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Authors and Affiliations

  1. Mihaela E. Sardiu and Michael P. Washburn are at Stowers Institute for Medical Research, Kansas City, Missouri, USA.,

    Mihaela E Sardiu & Michael P Washburn

Authors
  1. Mihaela E Sardiu
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  2. Michael P Washburn
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Correspondence to Michael P Washburn.

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Sardiu, M., Washburn, M. Enriching quantitative proteomics with SIN. Nat Biotechnol 28, 40–42 (2010). https://doi.org/10.1038/nbt0110-40

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