Skip to main content
SpringerLink
Log in

Laser surgery for mouse geneticists

  • News & Views
  • Published:

From Nature Biotechnology

View current issue Submit your manuscript

A rapid, new approach for generating mutant mice from embryonic stem cells may accelerate high-throughput phenotype analysis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Comparison of homozygous mutant mouse production by conventional and laser-assisted microinjection procedures.

Kim Caesar

References

  1. Austin, C.P. et al. Nat. Genet. 36, 921–924 (2004).

    Article  CAS  Google Scholar 

  2. Auwerx, J. et al. Nat. Genet. 36, 925–927 (2004).

    Article  CAS  Google Scholar 

  3. Poueymirou, W.T. et al. Nat. Biotechnol. 25, 91–99 (2007).

    Article  CAS  Google Scholar 

  4. Eggan, K. et al. Nat. Biotechnol. 20, 455–459 (2002).

    Article  CAS  Google Scholar 

  5. Tokunaga, T. & Tsunoda, Y. Dev. Growth Differ. 34, 561–566 (1992).

    Article  Google Scholar 

  6. Mortensen, R.M., Conner, D.A., Chao, S., Geisterfer-Lowrance, A.A. & Seidman, J.G. Mol. Cell. Biol. 12, 2391–2395 (1992).

    Article  CAS  Google Scholar 

  7. Abuin, A. & Bradley, A. Mol. Cell. Biol. 16, 1851–1856 (1996).

    Article  CAS  Google Scholar 

  8. Brook, F.A. & Gardner, R.L. Proc. Natl. Acad. Sci. USA 94, 5709–5712 (1997).

    Article  CAS  Google Scholar 

  9. Schoonjans, L. et al. Stem Cells 21, 90–97 (2003).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Jackson Laboratory, Bar Harbor, 04609, Maine, USA

    Thomas Gridley & Rick Woychik

Authors
  1. Thomas Gridley
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rick Woychik
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gridley, T., Woychik, R. Laser surgery for mouse geneticists. Nat Biotechnol 25, 59–60 (2007). https://doi.org/10.1038/nbt0107-59

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0107-59

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation