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Challenges in modeling the human gut microbiome

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Figure 1: The growth simulations for the AGORA and BiGG models.
Figure 2: The blocked reactions and reactions involved in thermodynamically infeasible loops in 100 models.
Figure 3

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Acknowledgements

We acknowledge funding from the Novo Nordisk Foundation (NNF10CC1016517) and the Knut and Alice Wallenberg Foundation.

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Authors and Affiliations

  1. Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

    Parizad Babaei, Boyang Ji & Jens Nielsen

  2. Centre for Host–Microbiome Interactions, Dental Institute, King's College London, London, UK

    Saeed Shoaie

  3. Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark

    Jens Nielsen

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  1. Parizad Babaei
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  2. Saeed Shoaie
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  3. Boyang Ji
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  4. Jens Nielsen
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Correspondence to Jens Nielsen.

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Supplementary Text and Figures

Supplementary Figures 1–11 and Supplementary Tables 1 and 2 (PDF 10901 kb)

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Babaei, P., Shoaie, S., Ji, B. et al. Challenges in modeling the human gut microbiome. Nat Biotechnol 36, 682–686 (2018). https://doi.org/10.1038/nbt.4213

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