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Genome editing for clinical HIV isolates

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An engineered recombinase removes the HIV-1 provirus from patient-derived cells and reduces infection in humanized mice.

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Figure 1: Summary of the current HIV-1 cure strategies and their primary obstacles.

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Authors and Affiliations

  1. Michelle Kim and Robert F. Siliciano are at Johns Hopkins University School of Medicine and Howard Hughes Medical Institute, Baltimore, Maryland, USA.,

    Michelle Kim & Robert F Siliciano

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  1. Michelle Kim
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  2. Robert F Siliciano
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Correspondence to Robert F Siliciano.

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The authors declare no competing financial interests.

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Kim, M., Siliciano, R. Genome editing for clinical HIV isolates. Nat Biotechnol 34, 388–389 (2016). https://doi.org/10.1038/nbt.3531

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