References
Paul, D.S., Soranzo, N. & Beck, S. Bioessays 36, 191–199 (2014).
Ritchie, G.R., Dunham, I., Zeggini, E. & Flicek, P. Nat. Methods 11, 294–296 (2014).
Bernstein, B.E. et al. Nat. Biotechnol. 28, 1045–1048 (2010).
ENCODE Project Consortium. Nature 489, 57–74 (2012).
Chadwick, L.H. Epigenomics 4, 317–324 (2012).
Zhou, X., Li, D., Lowdon, R.F., Costello, J.F. & Wang, T. Bioinformatics 30, 2206–2207 (2014)
Zhou, X. et al. Nat. Methods 10, 375–376 (2013).
Zhou, X. et al. Nat. Methods 8, 989–990 (2011).
Roadmap Epigenomics Consortium et al. Nature doi:10.1038/nature14248 (18 February 2015).
Sawcer, S. et al. Nature 476, 214–219 (2011).
Compston, A. & Coles, A. Lancet 359, 1221–1231 (2002).
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Supplementary Text and Figures
Supplementary Notes and Supplementary Figures 1–9 (PDF 3621 kb)
Supplementary Tutorial 1
Tutorial: Using the Roadmap EpiGenome Browser to explore integrated human epigenomics resources and annotate genetic variants (PDF 6659 kb)
Supplementary Tutorial 2
Tutorial: Cloning the Roadmap EpiGenome Browser on Amazon Cloud (PDF 2010 kb)
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Zhou, X., Li, D., Zhang, B. et al. Epigenomic annotation of genetic variants using the Roadmap Epigenome Browser. Nat Biotechnol 33, 345–346 (2015). https://doi.org/10.1038/nbt.3158
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DOI: https://doi.org/10.1038/nbt.3158
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