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RNA sequencing in situ

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Using a cell as an RNA sequencing chip enables spatial analyses of the transcriptome at subcellular resolution.

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Figure 1: Choosing the proper assay for gene expression involves trade-offs on parameters such as throughput or positional resolution.

Debbie Maizels/Nature Publishing Group

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Correspondence to Arjun Raj.

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Ginart, P., Raj, A. RNA sequencing in situ. Nat Biotechnol 32, 543–544 (2014). https://doi.org/10.1038/nbt.2921

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