Skip to main content
SpringerLink
Log in

Defining the path to hematopoietic stem cells

  • News & Views
  • Published:

From Nature Biotechnology

View current issue Submit your manuscript

New insights into hemogenic endothelium will facilitate efforts to produce hematopoietic stem cells in vitro.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: A model depicting the development of hemogenic endothelium from PSCs.

References

  1. Choi, K.D. et al. Cell Reports 2, 553–567 (2012).

    Article  CAS  Google Scholar 

  2. Rafii, S. et al. Blood 121, 770–780 (2013).

    Article  CAS  Google Scholar 

  3. Nakajima-Takagi, Y. et al. Blood 121, 447–458 (2013).

    Article  CAS  Google Scholar 

  4. Kim, P.G. et al. Proc. Natl. Acad. Sci. USA 110, E141–E150 (2013).

    Article  CAS  Google Scholar 

  5. Kennedy, M. et al. Cell Reports 2, 1722–1735 (2012).

    Article  CAS  Google Scholar 

  6. Lee, D. et al. Cell Stem Cell 2, 497–507 (2008).

    Article  CAS  Google Scholar 

  7. Medvinsky, A., Rybtsov, S. & Taoudi, S. Development 138, 1017–1031 (2011).

    Article  CAS  Google Scholar 

  8. Antas, V.I., Al-Drees, M.A., Prudence, A.J., Sugiyama, D. & Fraser, S.T. Int. J. Biochem. Cell Biol. 45, 692–695 (2013).

    Article  CAS  Google Scholar 

  9. Choi, E. et al. Stem Cells 30, 2297–2308 (2012).

    Article  CAS  Google Scholar 

  10. Chen, M.J., Yokomizo, T., Zeigler, B.M., Dzierzak, E. & Speck, N.A. Nature 457, 887–891 (2009).

    Article  CAS  Google Scholar 

  11. Lancrin, C. et al. Nature 457, 892–895 (2009).

    Article  CAS  Google Scholar 

  12. Kaimakis, P., Crisan, M. & Dzierzak, E. Biochim. Biophys. Acta 1830, 2395–2403 (2013).

    Article  CAS  Google Scholar 

  13. Adamo, L. et al. Nature 459, 1131–1135 (2009).

    Article  CAS  Google Scholar 

  14. Fitch, S.R. et al. Cell Stem Cell 11, 554–566 (2012).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Christopher M. Sturgeon, Andrea Ditadi, Raedun L. Clarke and Gordon Keller are at the McEwen Centre for Regenerative Medicine, University Health Network, Toronto, Ontario, Canada.,

    Christopher M Sturgeon, Andrea Ditadi, Raedun L Clarke & Gordon Keller

Authors
  1. Christopher M Sturgeon
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Andrea Ditadi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Raedun L Clarke
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Gordon Keller
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gordon Keller.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sturgeon, C., Ditadi, A., Clarke, R. et al. Defining the path to hematopoietic stem cells. Nat Biotechnol 31, 416–418 (2013). https://doi.org/10.1038/nbt.2571

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.2571

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation