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High-efficiency TALEN-based gene editing produces disease-resistant rice

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Figure 1: High-efficiency targeted gene editing using TALENs.

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Acknowledgements

We thank D. Wright and C. Yao for helpful suggestions, L. Xue and J. Luo for technical assistance, and F.F. White and S. Howell for critical reading of the manuscript. This work was supported by grants from the US National Science Foundation (0820831 to B.Y., MCB-0952323 to M.H.S., and MCB-0952533 and EPSCoR grant 1004094 to D.P.W.).

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Authors and Affiliations

  1. Department of Genetics, Development & Cell Biology, Iowa State University, Ames, Iowa, USA

    Ting Li, Bo Liu, Martin H Spalding & Bing Yang

  2. Department of Biochemistry, University of Nebraska–Lincoln, Lincoln, Nebraska, USA

    Donald P Weeks

Authors
  1. Ting Li
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  2. Bo Liu
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  3. Martin H Spalding
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  4. Donald P Weeks
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  5. Bing Yang
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Correspondence to Bing Yang.

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Competing interests

T.L., B.L. and B.Y. are inventors on a patent application covering TALEN-mediated rice engineering for disease resistance.

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Supplementary Methods, Supplementary Note and Supplementary Figures 1-11 (PDF 580 kb)

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Li, T., Liu, B., Spalding, M. et al. High-efficiency TALEN-based gene editing produces disease-resistant rice. Nat Biotechnol 30, 390–392 (2012). https://doi.org/10.1038/nbt.2199

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