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An infrared fluorescent protein for deeper imaging

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A newly engineered infrared fluorescent protein will allow microscopists to peer more deeply into living animals.

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Figure 1: Absorption and scattering lengths are longer for near-infrared compared with visible light.

References

  1. Chalfie, M., Tu, Y., Euskirchen, G., Ward, W.W. & Prasher, D.C. Science 263, 802–805 (1994).

    Article  CAS  PubMed  Google Scholar 

  2. Shaner, N.C., Steinbach, P.A. & Tsien, R.Y. Nat. Methods 2, 905–909 (2005).

    Article  CAS  PubMed  Google Scholar 

  3. Filonov, G.S. et al. Nat. Biotechnol. 29, 757–761 (2011).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Shu, X. et al. Science 324, 804–807 (2009).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Helmchen, F. & Denk, W. Nat. Methods 2, 932–940 (2005).

    Article  CAS  PubMed  Google Scholar 

  6. Ntziachristos, V. Annu. Rev. Biomed. Eng. 8, 1–33 (2006).

    Article  CAS  PubMed  Google Scholar 

  7. Tsien, R. Y. Cold Spring Harb. Protoc. 2009, pdb top57 (2009).

  8. Zijlstra, W.G., Buursma, A. & Meeuwsen-van der Roest, W.P. Clin. Chem. 37, 1633–1638 (1991).

    Article  CAS  PubMed  Google Scholar 

  9. Matcher, S.J., Cope, M. & Delpy, D.T. Phys. Med. Biol. 39, 177–196 (1994).

    Article  CAS  PubMed  Google Scholar 

  10. Bashkatov, A.N.G., Kochubey, E.A. & Tuchin, V.I. Appl. Phys. (Berl.) 38, 2543–2555 (2005).

    CAS  Google Scholar 

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Correspondence to Mark J Schnitzer.

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Lecoq, J., Schnitzer, M. An infrared fluorescent protein for deeper imaging. Nat Biotechnol 29, 715–716 (2011). https://doi.org/10.1038/nbt.1941

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