Efforts to treat brain tumours by targeting cancer cells have had only modest clinical success. It emerges that targeting a protein secreted from neurons adjacent to the tumour might be a useful alternative approach. See Letter p.533
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References
Ostrom, Q. T. et al. Neuro-Oncology 18, Suppl. 5 (2016).
Venkatesh, H. S. et al. Nature 549, 533–537 (2017).
Stupp, R. et al. J. Am. Med. Assoc. 314, 2535–2543 (2015).
Stupp, R. et al. N. Engl. J. Med. 352, 987–996 (2005).
Vredenburgh, J. J. et al. J. Clin. Oncol. 25, 4722–4729 (2007).
Gibson, E. M. et al. Science 344, 1252304 (2014).
Venkatesh, H. S. et al. Cell 161, 803–816 (2015).
Witters, L. et al. Cancer Res. 68, 7083–7089 (2008).
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Taylor, M., Ramaswamy, V. Drain the swamp to beat glioma. Nature 549, 460–461 (2017). https://doi.org/10.1038/nature24141
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DOI: https://doi.org/10.1038/nature24141
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