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Keeping it real to kill glioblastoma

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The results of in vitro and in vivo screens to identify genes that are essential for the survival of a type of brain cancer show almost no overlap, underlining the need for caution when interpreting in vitro studies. See Letter p355.

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Figure 1: Parallel screens for essential genes.

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Correspondence to Paul A. Northcott.

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Northcott, P. Keeping it real to kill glioblastoma. Nature 547, 291–292 (2017). https://doi.org/10.1038/nature23095

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