Skip to main content
SpringerLink
Log in

Cancer

Tumours build their niche

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

It emerges that tumour cells can give rise to non-dividing cells that form part of the supporting microenvironment known as the niche. These niche cells secrete proteins that drive tumour growth and progression. See Letters p.355 & p.360

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Tumour cells and their niche.

Notes

  1. See all news & views

References

  1. Tammela, T. et al. Nature 545, 355–359 (2017).

    Article  ADS  CAS  Google Scholar 

  2. Lim, J. S. et al. Nature 545, 360–364 (2017).

    Article  ADS  CAS  Google Scholar 

  3. Clevers, H. & Nusse, R. Cell 149, 1192–1205 (2012).

    Article  CAS  Google Scholar 

  4. Kadowaki, T., Wilder, E., Klingensmith, J., Zachary, K. & Perrimon, N. Genes Dev. 10, 3116–3128 (1996).

    Article  CAS  Google Scholar 

  5. Sato, T. E. Nature 469, 415–418 (2011).

    Article  ADS  CAS  Google Scholar 

  6. Hayward, P., Kalmar, T. & Martinez Arias, A. Development 135, 411–424 (2008).

    Article  CAS  Google Scholar 

  7. Koch, U. & Radtke, F. Cell. Mol. Life Sci. 64, 2746–2762 (2007).

    Article  CAS  Google Scholar 

  8. Sutherland, K. D. et al. Cancer Cell 19, 754–764 (2011).

    Article  CAS  Google Scholar 

  9. Morimoto, M., Nishinakamura, R., Saga, Y. & Kopan, R. Development 139, 4365–4373 (2012).

    Article  CAS  Google Scholar 

  10. Noguchi, M., Sumiyama, K. & Morimoto, M. Cell Rep. 13, 2679–2686 (2015).

    Article  CAS  Google Scholar 

  11. Guha, A., Deshpande, A., Jain, A., Sebastiani, P. & Cardoso, W. V. Cell Rep. 19, 246–254 (2017).

    Article  CAS  Google Scholar 

  12. Pardo-Saganta, A. et al. Nature 523, 597–601 (2015).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gurdon Institute, University of Cambridge, Cambridge, CB2 1QN, UK

    Meritxell Huch & Emma L. Rawlins

  2. Wellcome Trust – Medical Research Council Stem Cell Institute, Cambridge

    Meritxell Huch & Emma L. Rawlins

Authors
  1. Meritxell Huch
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Emma L. Rawlins
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Meritxell Huch or Emma L. Rawlins.

Related links

Related links

Related links in Nature Research

Cancer: Tumour stem-cell surprises

Cancer: Double trouble for tumours

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Huch, M., Rawlins, E. Tumours build their niche. Nature 545, 292–293 (2017). https://doi.org/10.1038/nature22494

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature22494

  • Springer Nature Limited

Search

Navigation