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Ageing

Tools to eliminate senescent cells

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Ageing and many diseases are partly driven by the accumulation of damaged cells that no longer divide. It emerges that these senescent cells can be eradicated in mice using a drug that interferes with the activity of the protein FOXO4.

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Figure 1: Targeting a damaged cell population.

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Correspondence to Manuel Serrano.

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Serrano, M. Tools to eliminate senescent cells. Nature 545, 294–295 (2017). https://doi.org/10.1038/nature22493

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