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Molecular genetics

Chaperone protein gets personal

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Two studies of the molecular chaperone protein HSP90 reveal how complex traits can be shaped by genetic and environmental context. This work highlights the challenges of personalized medicine.

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Figure 1: Heat-shock protein 90 (HSP90) alters the effects of genetic differences.

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Correspondence to Mark L. Siegal.

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Siegal, M. Chaperone protein gets personal. Nature 545, 36–37 (2017). https://doi.org/10.1038/nature22487

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