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Messenger RNAs marked for longer life

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A molecular modification called m6Am has been found to regulate the stability of messenger RNAs in mammalian cells. The mechanism casts fresh light on how reversibly modified RNA bases control the fate of mRNA. See Article p.371

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Figure 1: The m6Am modification confers stability on messenger RNAs.

Change history

  • 04 January 2017

    The final sentence contained a chemical inaccuracy that has now been corrected.

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Author notes

  1. John D. Gross is in the Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California 94143, USA.

Authors and Affiliations

  1. David E. Weinberg is in the Department of Cellular and Molecular Pharmacology, and in the Sandler Faculty Fellows Program, University of California, San Francisco, San Francisco, California 94143, USA.,

    David E. Weinberg & John D. Gross

Authors
  1. David E. Weinberg
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  2. John D. Gross
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Corresponding author

Correspondence to David E. Weinberg.

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Weinberg, D., Gross, J. Messenger RNAs marked for longer life. Nature 541, 293–294 (2017). https://doi.org/10.1038/nature21109

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