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Figure 1: Consistency between drug sensitivity measures (AUC) across FIMM, CGP and CCLE.

References

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Authors and Affiliations

  1. Princess Margaret Cancer Centre, University Health Network, Toronto, M5G 2M9, Ontario, Canada

    Zhaleh Safikhani, Petr Smirnov, Mark Freeman & Benjamin Haibe-Kains

  2. Department of Medical Biophysics, University of Toronto, Toronto, M5G 1L7, Ontario, Canada

    Zhaleh Safikhani & Benjamin Haibe-Kains

  3. Institut de recherches cliniques de Montréal, Montreal, H2W 1R7, Quebec, Canada

    Nehme El-Hachem

  4. Hospital for Sick Children, Toronto, M5G 1X8, Ontario, Canada

    Anna Goldenberg

  5. Department of Computer Science, University of Toronto, Toronto, M5S 2E4, Ontario, Canada

    Anna Goldenberg & Benjamin Haibe-Kains

  6. The Francis Crick Institute, London, NW1 1AT, UK

    Nicolai J. Birkbak

  7. University College London Cancer Institute, London, WC1E 6BT, UK

    Nicolai J. Birkbak

  8. Beth Israel Deaconess Medical Center, Boston, 02215, Massachusetts, USA

    Andrew H. Beck

  9. Harvard Medical School, Boston, 02115, Massachusetts, USA

    Andrew H. Beck & Hugo J. W. L. Aerts

  10. Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA

    Hugo J. W. L. Aerts & John Quackenbush

  11. Brigham and Women’s Hospital, Boston, 02115, Massachusetts, USA

    Hugo J. W. L. Aerts

  12. Harvard TH Chan School of Public Health, Boston, 02115, Massachusetts, USA

    John Quackenbush

  13. Ontario Institute of Cancer Research, Toronto, M5G 1L7, Ontario, Canada

    Benjamin Haibe-Kains

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  1. Zhaleh Safikhani
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Supplementary information

Supplementary Information

This file contains Supplementary Methods, Supplementary Text and Data, Supplementary Figure 1 and additional references. (PDF 305 kb)

Supplementary Data 1

This file shows drug dose-response curves from the FIMM dataset. When the same drug was tested on the same cell line in CGP and/or CCLE, the curves were also displayed for comparison. (PDF 1564 kb)

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Safikhani, Z., El-Hachem, N., Smirnov, P. et al. Safikhani et al. reply. Nature 540, E6–E8 (2016). https://doi.org/10.1038/nature20172

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