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Parkinson's disease

Guilt by genetic association

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Certain sequence variants of the α-synuclein gene are linked to the risk of Parkinson's disease. An analysis of these variants using gene-editing technology provides a possible explanation for this increased risk. See Letter p.95

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Figure 1: A CRISPR cross-examination.

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Authors and Affiliations

  1. Asa Abeliovich and Herve Rhinn are in the Departments of Pathology, Cell Biology and Neurology, and the Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York 10032, USA.,

    Asa Abeliovich & Herve Rhinn

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  1. Asa Abeliovich
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  2. Herve Rhinn
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Corresponding author

Correspondence to Asa Abeliovich.

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Competing interests

A.A. is a co-founder and consultant for Alector, a biotechnology company. H.R. is a consultant for Alector.

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Abeliovich, A., Rhinn, H. Guilt by genetic association. Nature 533, 40–41 (2016). https://doi.org/10.1038/nature17891

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