Skip to main content
Log in

Synthetic biology

Ribosomal ties that bind

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

The ribosome is the cellular complex of proteins and RNA molecules that synthesizes proteins. An artificial ribosome in which the two main subunits are tethered together creates opportunities for engineering this process. See Letter p.119

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: A tethered ribosome.

Notes

  1. See all news & views

References

  1. Orelle, C. et al. Nature 524, 119–124 (2015).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Ramakrishnan, V. Cell 159, 979–984 (2014).

    Article  CAS  PubMed  Google Scholar 

  3. Bock, L. V. et al. Nature Struct. Mol. Biol. 20, 1390–1396 (2013).

    Article  CAS  Google Scholar 

  4. Petrov, A., Chen, J., O'Leary, S., Tsai, A. & Puglisi, J. D. Cold Spring Harb. Perspect. Biol. 4, a011551 (2012).

    Article  PubMed  PubMed Central  Google Scholar 

  5. O'Donoghue, P., Ling, J., Wang, Y. S. & Soll, D. Nature Chem. Biol. 9, 594–598 (2013).

    Article  CAS  Google Scholar 

  6. Hui, A. & de Boer, H. A. Proc. Natl Acad. Sci. USA 84, 4762–4766 (1987).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  7. Marshall, R. A., Dorywalska, M. & Puglisi, J. D. Proc. Natl Acad. Sci. USA 105, 15364–15369 (2008).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  8. Dorywalska, M. et al. Nucleic Acids Res. 33, 182–189 (2005).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Joseph D. Puglisi.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Puglisi, J. Ribosomal ties that bind. Nature 524, 45–46 (2015). https://doi.org/10.1038/nature14642

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature14642

  • Springer Nature Limited

Navigation