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An extravascular route for tumour cells

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Molecular tracing of populations of breast-cancer cells in a primary tumour in mice reveals that two proteins, Serpine2 and Slpi, enable tumour cells to form vascular-like networks, facilitating perfusion and metastasis. See Letter p.358

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Figure 1: Vascular mimicry drives metastasis.

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Authors and Affiliations

  1. Mary J. C. Hendrix is at the Stanley Manne Children's Research Institute, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611–2605, USA.,

    Mary J. C. Hendrix

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  1. Mary J. C. Hendrix
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Correspondence to Mary J. C. Hendrix.

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Hendrix, M. An extravascular route for tumour cells. Nature 520, 300–302 (2015). https://doi.org/10.1038/nature14382

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