Skip to main content
Log in

Microbiology

How bacteria get spacers from invaders

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Bacteria use CRISPR–Cas systems to develop immunity to viruses. Details of how these systems select viral DNA fragments and integrate them into bacterial DNA to create a memory of invaders have now been reported. See Articles p.193 & p.199

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: The bacterial immune response.

Notes

  1. See all news & views

References

  1. Barrangou, R. et al. Science 315, 1709–1712 (2007).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Brouns, S. J. J. et al. Science 321, 960–964 (2008).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  3. Yosef, I., Goren, M. G. & Qimron, U. Nucleic Acids Res. 40, 5569–5576 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Heller, R. et al. Nature 519, 199–202 (2015).

    Article  ADS  Google Scholar 

  5. Nuñez, J. K., Lee, A. S. Y., Engelman, A. & Doudna, J. A. Nature 519, 193–198 (2015).

    Article  ADS  PubMed  PubMed Central  Google Scholar 

  6. Mojica, F. J. M., Díez-Villaseñor, C., García-Martínez, J. & Almendros, C. Microbiology 155, 733–740 (2009).

    Article  CAS  PubMed  Google Scholar 

  7. Datsenko, K. A. et al. Nature Commun. 3, 945; http://dx.doi.org/10.1038/ncomms1937 (2012).

    Article  ADS  Google Scholar 

  8. Swarts, D. C., Mosterd, C., van Passel, M. W. & Brouns, S. J. J. PLoS ONE 7, e35888 (2012).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  9. Arslan, Z., Hermanns, V., Wurm, R., Wagner, R. & Pul, U. Nucleic Acids Res. 42, 7884–7893 (2014).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Nuñez, J. K. et al. Nature Struct. Mol. Biol. 21, 528–534 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Udi Qimron.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yosef, I., Qimron, U. How bacteria get spacers from invaders. Nature 519, 166–167 (2015). https://doi.org/10.1038/nature14204

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature14204

  • Springer Nature Limited

This article is cited by

Navigation