Certain structural elements allow messenger RNAs not usually processed by the protein-synthesis apparatus to be translated. It now seems that they also control the expression of genes involved in embryonic development. See Article p.33
References
Mirsky, A. E. & Ris, H. J. Gen. Physiol. 34, 451–462 (1951).
Mallo, M. & Alonso, C. R. Development 140, 3951–3963 (2013).
Xue, S. et al. Nature 517, 33–38 (2015).
Hershey, J. W. B., Sonenberg, N. & Mathews, M. B. Cold Spring Harb. Perspect. Biol. 4, a011528 (2012).
Sonenberg, N. & Hinnebusch, A. G. Cell 136, 731–745 (2009).
Mokrejš, M. et al. Nucleic Acids Res. 38 (Suppl. 1), D131–D136 (2010).
Alexander, T., Nolte, C. & Krumlauf, R. Annu. Rev. Cell Dev. Biol. 25, 431–456 (2009).
Kondrashov, N. et al. Cell 145, 383–397 (2011).
Jenner, L. et al. Curr. Opin. Struct. Biol. 22, 759–767 (2012).
Giaever, G. et al. Nature 418, 387–391 (2002).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Dinman, J. Entry signals control development. Nature 517, 24–25 (2015). https://doi.org/10.1038/nature14069
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature14069
- Springer Nature Limited