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The mixed blessing of interferon

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A study in monkeys finds that treatment with the protein interferon protects against simian immunodeficiency virus, but that prolonged interferon administration exacerbates the chronic stage of the infection. See Letter p.601

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Figure 1: Interferon in acute and chronic infection.

References

  1. Longo, D. L. et al. Ann. NY Acad. Sci. 437, 421–430 (1984).

    Article  CAS  ADS  Google Scholar 

  2. Sandler, G. N. et al. Nature 511, 601–605 (2014).

    Article  CAS  ADS  Google Scholar 

  3. Schoggins, J. W. Curr. Opin. Virol. 6C, 40–46 (2014).

    Article  Google Scholar 

  4. Harris, R. S., Hultquist, J. F. & Evans, D. T. J. Biol. Chem. 287, 40875–40883 (2012).

    Article  CAS  Google Scholar 

  5. Asmuth, D. M. et al. J. Infect. Dis. 201, 1686–1696 (2010).

    Article  CAS  Google Scholar 

  6. Torriani, F. J. et al. N. Engl. J. Med. 351, 438–450 (2004).

    Article  CAS  Google Scholar 

  7. Borden, E. C. & Murphy, F. A. J. Immunol. 106, 134–142 (1971).

    CAS  PubMed  Google Scholar 

  8. Rotger, M. et al. PLoS Pathog. 6, e1000781 (2010).

    Article  Google Scholar 

  9. Bosinger, S. E. et al. J. Clin. Invest. 119, 3556–3572 (2009).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Fenton-May, A. E. et al. Retrovirology 10, 146 (2013).

    Article  Google Scholar 

  11. Ivashkiv, L. B. & Donlin, L. T. Nature Rev. Immunol. 14, 36–49 (2014).

    Article  CAS  Google Scholar 

  12. Medzhitov, R., Schneider, D. S. & Soares, M. P. Science 335, 936–941 (2012).

    Article  CAS  ADS  Google Scholar 

  13. Rotger, M. et al. J. Clin. Invest. 121, 2391–2400 (2011).

    Article  CAS  Google Scholar 

  14. Rausell, A., McLaren, P. J. & Telenti, A. F1000Prime Rep. 5, 29 (2013).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Amalio Telenti is at the Institute of Microbiology, University Hospital of Lausanne, University of Lausanne, 1011 Lausanne, Switzerland.,

    Amalio Telenti

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  1. Amalio Telenti
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Correspondence to Amalio Telenti.

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Telenti, A. The mixed blessing of interferon. Nature 511, 537–538 (2014). https://doi.org/10.1038/nature13517

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