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Darwinian tumour suppression

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Competition for access to a survival factor has been found to explain why incoming cells from the bone marrow replace resident cells in the thymus. Reducing this competition can cause tumours to form. See Article p.465

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Figure 1: Cellular competition prevents tumour formation.

References

  1. Martins, V. C. et al. Nature 509, 465–470 (2014).

    Article  ADS  CAS  Google Scholar 

  2. Frey, J. R., Ernst, B., Surh, C. D. & Sprent, J. J. Exp. Med. 175, 1067–1071 (1992).

    Article  CAS  Google Scholar 

  3. Moreno, E., Basler, K. & Morata, G. Nature 416, 755–759 (2002).

    Article  ADS  CAS  Google Scholar 

  4. Raff, M. C. Nature 356, 397–400 (1992).

    Article  ADS  CAS  Google Scholar 

  5. Jiang, Q. et al. Mol. Cell. Biol. 24, 6501–6513 (2004).

    Article  CAS  Google Scholar 

  6. Martins, V. C. et al. J. Exp. Med. 209, 1409–1417 (2012).

    Article  CAS  Google Scholar 

  7. Rhiner, C. et al. Dev. Cell 18, 985–998 (2010).

    Article  CAS  Google Scholar 

  8. Merino, M. M., Rhiner, C., Portela, M. & Moreno, E. Curr. Biol. 23, 1300–1309 (2013).

    Article  CAS  Google Scholar 

  9. Patel, P. H. & Edgar, B. A. Semin. Cell Dev. Biol. http://dx.doi.org/10.1016/j.semcdb.2014.03.012 (2014).

  10. Vincent, J.-P., Fletcher, A. G. & Baena-Lopez, L. A. Nature Rev. Mol. Cell Biol. 14, 581–591 (2013).

    Article  CAS  Google Scholar 

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  1. Eduardo Moreno is at the Institute of Cell Biology, IZB, University of Bern, Bern CH-3012, Switzerland.,

    Eduardo Moreno

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  1. Eduardo Moreno
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Correspondence to Eduardo Moreno.

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Moreno, E. Darwinian tumour suppression. Nature 509, 435–436 (2014). https://doi.org/10.1038/nature13337

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