The discovery of long non-coding RNAs that control the liaisons between a transcription factor with a key role in prostate cancer and its target genes sheds light on how RNAs dictate information flow in the cell nucleus. See Letter p.598
Notes
*This article and the paper under discussion1 were published online on 14 August 2013.
References
Yang, L. et al. Nature 500, 598–602 (2013).
Ryan, C. J. & Tindall, D. J. J. Clin. Oncol. 29, 3651–3658 (2011).
Guttman, M. et al. Nature 477, 295–300 (2011).
Batista, P. J. & Chang, H. Y. Cell 152, 1298–1307 (2013).
Prensner, J. R. et al. Nature Biotechnol. 29, 742–749 (2011).
Chu, C., Qu, K., Zhong, F. L., Artandi, S. E. & Chang, H. Y. Mol. Cell 44, 667–678 (2011).
Lai, F. et al. Nature 494, 497–501 (2013).
Brunner, A. L. et al. Genome Biol. 13, R75 (2012).
Sharma, N. L. et al. Cancer Cell 23, 35–47 (2013).
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Schmitt, A., Chang, H. Long RNAs wire up cancer growth. Nature 500, 536–537 (2013). https://doi.org/10.1038/nature12548
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DOI: https://doi.org/10.1038/nature12548
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