Retrieving a memory initiates a window of vulnerability for that memory. Simple behavioural methods can modify distressing memories during this window, eliminating fear reactions to traumatic reminders.
Notes
*This article and the paper under discussion were published online on 9 December 2009.
References
Nader, K. M., Schafe, G. E. & Le Doux, J. E. Nature 406, 722–726 (2000).
Schiller, D. et al. Nature 463, 49–53 (2010).
McGaugh, J. L. Science 287, 248–251 (2000).
Nader, K. & Hardt, O. Nature Rev. Neurosci. 10, 224–234 (2009).
Alberini, C. M. Trends Neurosci. 28, 51–56 (2005).
Monfils, M.-H., Cowansage, K. K., Klann, E. & LeDoux, J. E. Science 324, 951–955 (2009).
Milad, M. R. et al. Biol. Psychiatry 66, 1075–1082 (2009).
Davis, M., Ressler, K., Rothbaum, B. O. & Richardson, R. Biol. Psychiatry 60, 369–375 (2006).
Brunet, A. et al. J. Psychiatr. Res. 42, 503–506 (2008).
Kindt, M., Soeter, M. & Vervliet, B. Nature Neurosci. 12, 256–258 (2009).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Quirk, G., Milad, M. Editing out fear. Nature 463, 36–37 (2010). https://doi.org/10.1038/nature08767
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature08767
- Springer Nature Limited