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Cell biology

Taking a turn into the nucleus

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How soluble proteins get into the cell nucleus is known in great detail, but how membrane proteins make it into the inner nuclear membrane has long been an enigma. The two processes in fact turn out to be related.

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Figure 1: Receptor-mediated transport of proteins to the inner nuclear membrane (INM).

References

  1. King, M. C., Lusk, C. P. & Blobel, G. Nature 442, 1003–1007 (2006).

    Article  ADS  CAS  Google Scholar 

  2. Ellenberg, J. et al. J. Cell Biol. 138, 1193–1206 (1997).

    Article  CAS  Google Scholar 

  3. Smith, S. & Blobel, G. J. Cell Biol. 120, 631–637 (1993).

    Article  CAS  Google Scholar 

  4. Soullam, B. & Worman, H. J. J. Cell Biol. 120, 1093–1100 (1993).

    Article  CAS  Google Scholar 

  5. Ohba, T., Schirmer, E. C., Nishimoto, T. & Gerace, L. J. Cell Biol. 167, 1051–1062 (2004).

    Article  CAS  Google Scholar 

  6. Saksena, S. et al. Nature Struct. Mol. Biol. 13, 500–508 (2006).

    Article  CAS  Google Scholar 

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Kutay, U., Mühlhäusser, P. Taking a turn into the nucleus. Nature 442, 991–992 (2006). https://doi.org/10.1038/nature05173

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