Accession codes
References
Pekarsky Y, Palamarchuk A, Maximov V, Efanov A, Nazaryan N, Santanam U et al. Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL. Proc Natl Acad Sci USA 2008; 105: 19643–19648.
Herling M, Patel KA, Khalili J, Schlette E, Kobayashi R, Medeiros LJ et al. TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state. Leukemia 2006; 20: 280–285.
Pekarsky Y, Santanam U, Cimmino A, Palamarchuk A, Efanov A, Maximov V et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006; 66: 11590–11593.
Lehmann S, Ogawa S, Raynaud SD, Sanada M, Nannya Y, Ticchioni M et al. Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia. Cancer 2008; 112: 1296–1305.
He X, He L, Hannon GJ . The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Res 2007; 67: 11099–11101.
van Dongen S, Abreu-Goodger C, Enright AJ . Detecting microRNA binding and siRNA off-target effects from expression data. Nat Methods 2008; 5: 1023–1025.
Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D et al. A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci USA 2008; 105: 13556–13561.
Zenz T, Mohr J, Eldering E, Kater AP, Buhler A, Kienle D et al. MiR-34a as part of the chemotherapy resistance network in chronic lymphocytic leukemia. Blood 2009; 113: 3801–3808.
Acknowledgements
We thank Dr HP Koeffler (Cedars-Sinai Medical Center, University of California at Los Angeles School of Medecine, Los Angeles, California) for helpful comments. This work was supported by the Institut National du Cancer (PL0079), and the European Community (MICROENVIMET, FP7-HEALTH-F2-2008-201279). We acknowledge the excellent support of the Nice-Sophia Antipolis Transcriptome Platform of the Marseille-Nice Genopole for the microarray experiments. We also thank Franck Aguila for artwork.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Cardinaud, B., Moreilhon, C., Marcet, B. et al. miR-34b/miR-34c: a regulator of TCL1 expression in 11q− chronic lymphocytic leukaemia?. Leukemia 23, 2174–2177 (2009). https://doi.org/10.1038/leu.2009.125
Published:
Issue Date:
DOI: https://doi.org/10.1038/leu.2009.125
- Springer Nature Limited
This article is cited by
-
miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction
Scientific Reports (2015)
-
The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival and clinical outcome in CLL
Leukemia (2015)
-
Epigenetic inactivation of mir-34b/c in addition to mir-34a and DAPK1 in chronic lymphocytic leukemia
Journal of Translational Medicine (2014)
-
Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia
Leukemia (2012)
-
Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway
Nature Cell Biology (2011)