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miR-34b/miR-34c: a regulator of TCL1 expression in 11q− chronic lymphocytic leukaemia?

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References

  1. Pekarsky Y, Palamarchuk A, Maximov V, Efanov A, Nazaryan N, Santanam U et al. Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL. Proc Natl Acad Sci USA 2008; 105: 19643–19648.

    Article  CAS  Google Scholar 

  2. Herling M, Patel KA, Khalili J, Schlette E, Kobayashi R, Medeiros LJ et al. TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state. Leukemia 2006; 20: 280–285.

    Article  CAS  Google Scholar 

  3. Pekarsky Y, Santanam U, Cimmino A, Palamarchuk A, Efanov A, Maximov V et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006; 66: 11590–11593.

    Article  CAS  Google Scholar 

  4. Lehmann S, Ogawa S, Raynaud SD, Sanada M, Nannya Y, Ticchioni M et al. Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia. Cancer 2008; 112: 1296–1305.

    Article  CAS  Google Scholar 

  5. He X, He L, Hannon GJ . The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Res 2007; 67: 11099–11101.

    Article  CAS  Google Scholar 

  6. van Dongen S, Abreu-Goodger C, Enright AJ . Detecting microRNA binding and siRNA off-target effects from expression data. Nat Methods 2008; 5: 1023–1025.

    Article  CAS  Google Scholar 

  7. Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D et al. A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci USA 2008; 105: 13556–13561.

    Article  CAS  Google Scholar 

  8. Zenz T, Mohr J, Eldering E, Kater AP, Buhler A, Kienle D et al. MiR-34a as part of the chemotherapy resistance network in chronic lymphocytic leukemia. Blood 2009; 113: 3801–3808.

    Article  CAS  Google Scholar 

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Acknowledgements

We thank Dr HP Koeffler (Cedars-Sinai Medical Center, University of California at Los Angeles School of Medecine, Los Angeles, California) for helpful comments. This work was supported by the Institut National du Cancer (PL0079), and the European Community (MICROENVIMET, FP7-HEALTH-F2-2008-201279). We acknowledge the excellent support of the Nice-Sophia Antipolis Transcriptome Platform of the Marseille-Nice Genopole for the microarray experiments. We also thank Franck Aguila for artwork.

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Cardinaud, B., Moreilhon, C., Marcet, B. et al. miR-34b/miR-34c: a regulator of TCL1 expression in 11q− chronic lymphocytic leukaemia?. Leukemia 23, 2174–2177 (2009). https://doi.org/10.1038/leu.2009.125

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