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Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts

  • Experimental Oncology
  • Published:
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Abstract

Tumour necrosis factor-alpha (TNF-alpha) reduced the interstitial fluid pressure (IFP) to 54-64% (P < 0.05) and the mean arterial blood pressure (MABP) to 70% (P < 0.01) of control values after 5 h in three human melanoma tumour lines transplanted to nude mice.

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Kristensen, C., Nozue, M., Boucher, Y. et al. Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts. Br J Cancer 74, 533–536 (1996). https://doi.org/10.1038/bjc.1996.397

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  • DOI: https://doi.org/10.1038/bjc.1996.397

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