Abstract
We determined the concentrations of immunoreactive epidermal growth factor in the urine (U-irEGF) of 97 adult patients with various malignancies, including carcinomas of the urinary bladder, kidney, stomach, colon, rectum, breast, endometrium, uterine cervix, ovary, vagina, prostate, pancreas and thyroid, liposarcoma and skin melanoma. The relative U-irEGF concentrations (ng m-1 creatinine) were higher (P = 0.002) for the whole series of female patients than for healthy controls matched for sex and age. Such difference did not appear for male patients. The only specific group with a statistically supranormal U-irEGF concentration (P = 0.0005) comprised women with endometrial carcinoma of the uterus.
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mattila, AL., Saario, I., Viinikka, L. et al. Urinary epidermal growth factor concentrations in various human malignancies. Br J Cancer 57, 139–141 (1988). https://doi.org/10.1038/bjc.1988.29
Issue Date:
DOI: https://doi.org/10.1038/bjc.1988.29
- Springer Nature Limited
This article is cited by
-
Quantitative SWATH-based proteomic profiling of urine for the identification of endometrial cancer biomarkers in symptomatic women
British Journal of Cancer (2023)
-
Immunoreactive low-molecular-weight epidermal growth factor in urine of patients with renal cell carcinoma
Urological Research (1992)
-
The level of urinary epidermal growth factor is not influenced by the extent of psoriatic lesions
Archives of Dermatological Research (1991)