Abstract
A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-.
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Maynard, P., Davies, C., Blamey, R. et al. Relationship between oestrogen-receptor content and histological grade in human primary breast tumours. Br J Cancer 38, 745–748 (1978). https://doi.org/10.1038/bjc.1978.282
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DOI: https://doi.org/10.1038/bjc.1978.282
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