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The path not taken

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If known pathways represent preferred paths through global protein networks, large-scale experiments should focus on how to recognize these paths among all of the alternatives.

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Figure 1: How do our traditional genetic and biochemical pathways measure up to the observed global co-expression and interaction networks?

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Marcotte, E. The path not taken. Nat Biotechnol 19, 626–627 (2001). https://doi.org/10.1038/90222

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