The events that enable polarization of T cells and migration across the vasculature to the target are largely unknown. New evidence suggests that PKC-β(I) may be pivotal in controlling this process.
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von Andrian, U. PKC-β(I): the whole ignition system or just a sparkplug for T cell migration?. Nat Immunol 2, 477–478 (2001). https://doi.org/10.1038/88660
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DOI: https://doi.org/10.1038/88660
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