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TREM-1: A new regulator of innate immunity in sepsis syndrome

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Abstract

Although we have drugs and biologics designed to interfere with the innate immune response, none has been shown to shut down the massive inflammatory reaction that occurs during sepsis. A new pro-inflammatory myeloid-cell receptor might make a better target.

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Figure 1: Some proteins likely to be involved in the myeloid cell response to LPS.

Bob Crimi

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Authors and Affiliations

  1. Department of Microbiology & Immunology, Weill Medical College Cornell University,

    Carl Nathan & Aihao Ding

Authors
  1. Carl Nathan
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  2. Aihao Ding
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Nathan, C., Ding, A. TREM-1: A new regulator of innate immunity in sepsis syndrome. Nat Med 7, 530–532 (2001). https://doi.org/10.1038/87846

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