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Pharmacogenetic applications of the Human Genome project

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Basic research and clinical studies are underway to identify genetic polymorphisms that underlie drug effects. What obstacles must we overcome before we can use genetic analysis to predict the ability of patients to respond to certain treatments?

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Figure 1: Application of human genetic diversity to pharmacogenetics.

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Liggett, S. Pharmacogenetic applications of the Human Genome project. Nat Med 7, 281–283 (2001). https://doi.org/10.1038/85411

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