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Impaired recognition and experience of disgust following brain injury

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Abstract

Huntington's disease can particularly affect people's recognition of disgust from facial expressions1,2, and functional neuroimaging research has demonstrated that facial expressions of disgust consistently engage different brain areas (insula and putamen) than other facial expressions3,4,5. However, it is not known whether these particular brain areas process only facial signals of disgust or disgust signals from multiple modalities. Here we describe evidence, from a patient with insula and putamen damage, for a neural system for recognizing social signals of disgust from multiple modalities.

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Figure 1: T1-weighted MR images showing a left hemisphere infarction involving the posterior part of the anterior insula, posterior insula, internal capsule, putamen and globus pallidus.

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Acknowledgements

We thank NK and his family for their time and assistance. Thanks also to Brian Cox for preparing the graphics.

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Authors and Affiliations

  1. MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge, CB2 2EF, UK

    Andrew J. Calder, Jill Keane & Facundo Manes

  2. Department of Radiology, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK

    Nagui Antoun

  3. Department of Psychology, University of York, Heslington, YO1 5DD, York, UK

    Andrew W. Young

Authors
  1. Andrew J. Calder
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  2. Jill Keane
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  3. Facundo Manes
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  4. Nagui Antoun
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  5. Andrew W. Young
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Correspondence to Andrew J. Calder.

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Calder, A., Keane, J., Manes, F. et al. Impaired recognition and experience of disgust following brain injury . Nat Neurosci 3, 1077–1078 (2000). https://doi.org/10.1038/80586

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  • DOI: https://doi.org/10.1038/80586

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