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Ibuprofen, inflammation and Alzheimer disease

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Mounting evidence suggests that non-steroidal anti-inflammatory drugs may be useful in reducing the risk of Alzheimer disease. After much study, the mechanism by which these drugs reduce the amyloid deposition associated with the disease is still open to speculation.

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Figure 1: Potential effects of ibuprofen on AD-type pathology.

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Wyss-Coray, T., Mucke, L. Ibuprofen, inflammation and Alzheimer disease. Nat Med 6, 973–974 (2000). https://doi.org/10.1038/79661

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