Marginal zone B cells may steal the limelight as the roles of Pyk-2 and BLyS begin to be elucidated. Pyk-2 deficiency leads to their loss whereas signaling via the BLyS receptor may augment their function.
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Bob Crimi
References
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Cyster, J. B cells on the front line. Nat Immunol 1, 9–10 (2000). https://doi.org/10.1038/76859
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DOI: https://doi.org/10.1038/76859
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