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Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells

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Figure 1: Presentation of gene trap vectors and integration sites.

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Acknowledgements

We thank A. von Holst for critically reading the manuscript; B. Skarnes and E. Ruley for pGT1.8 and U3βgeo gene trap vectors; S. Hennig and A. Hewelt for computer support; T. Gellert, A. Gatlik, S. Bourier, C. Werner, B. Schroeter, N. Lehmann, N. Daigle, T. Engist and B. Fella for expert technical assistance; and S. Rengsberger and A. Maier for secretarial work and artwork. This consortium has been supported by the Bundesministerium für Bildung und Forschung within the framework of the German Human Genome Project.

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Authors and Affiliations

  1. Max-Planck-Institute for Molecular Genetics, Berlin, Germany

    Michael V. Wiles, Patricia Ruiz & Hans Lehrach

  2. GSF-National Research Center for Environment and Health, Institute of Mammalian Genetics, Neuherberg, Germany

    Franz Vauti, Thomas Metz & Wolfgang Wurst

  3. Laboratory for Molecular Hematology, University of Frankfurt Medical School, Frankfurt am Main, Germany

    Jürgen Otte & Harald von Melchner

  4. Department of Developmental Biology, Max-Planck-Institute of Immunobiology, Freiburg, Germany

    Ernst-Martin Füchtbauer & Annette Füchtbauer

  5. Institute of Molecular and Structural Biology, Aarhus University, Aarhus, Denmark

    Ernst-Martin Füchtbauer

  6. Department of Cell and Molecular Biology, Institute of Biochemistry and Biotechnology, TU Braunschweig, Braunschweig, Germany

    Hans-Henning Arnold

  7. Max-Planck-Institute of Psychiatry, Molecular Neurogenetics , Munich, Germany

    Wolfgang Wurst

Authors
  1. Michael V. Wiles
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  2. Franz Vauti
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  7. Hans-Henning Arnold
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  8. Hans Lehrach
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  9. Thomas Metz
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  10. Harald von Melchner
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  11. Wolfgang Wurst
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Correspondence to Wolfgang Wurst.

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Wiles, M., Vauti, F., Otte, J. et al. Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet 24, 13–14 (2000). https://doi.org/10.1038/71622

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