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The new antibiotics

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Abstract

Can novel antibacterial treatments combat the rising tide of drug-resistant infections?

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Figure 1: Resistance is futile.

References

  1. Hancock, R.E.W. & Knowles, D. Are we approaching the end of the antibiotic era? Curr. Opin. Microbiol. 1, 493–494 (1998).

    Article  Google Scholar 

  2. http://www.phrma.org/.

  3. Strohl, W.R. (ed.) Biotechnology of antibiotics. (Marcel Dekker, New York, NY; 1997).

  4. Choudhury, D. et al. X-ray structure of the FimC–FimH chaperone–adhesin complex from uropathogenic Escherichia coli. Science 285, 1061–1066 (1999).

    Article  CAS  Google Scholar 

  5. Ganz T. & Lehrer R.I. Antimicrobial peptides of vertebrates. Curr. Opin. Immunol. 10, 41– 44 (1998).

    Article  CAS  Google Scholar 

  6. Valdovoa, R.H. & Falkow, S. Fluorescence-based isolation of bacterial genes expressed within host cells. Science 277, 2007–2011 (1997).

    Article  Google Scholar 

  7. Wilson, M. et al. Exploring drug-induced alteration in gene expression in Mycobacterium tuberculosis by microarray hybridization. Proc. Natl. Acad. Sci. USA 96, 12833–12838 (1999).

    Article  CAS  Google Scholar 

  8. Davies, J. Inactivation of antibiotics and the dissemination of resistance genes. Science 264, 375–382 ( 1994).

    Article  CAS  Google Scholar 

  9. Harvey, J. & Mason, L. The use and misuse of antibiotics in agriculture. Part 1. Current usage. (Soil Association, Bristol, UK; 1998).

    Google Scholar 

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Breithaupt, H. The new antibiotics. Nat Biotechnol 17, 1165–1169 (1999). https://doi.org/10.1038/70705

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